Description
The global increase of obesity and type 2 diabetes (T2DM) has epidemic proportions. Worldwide, an estimated 2.16 billions subjects are overweight or obese and 382 million people have diabetes, a number that will rise to 592 million by 2035. This pandemic may portend severe consequences in Nephrology. Thus, an accurate evaluation of renal function and a proper identification of the risk of renal disease are both crucial in patients with diabetes and obesity. In this course we will discuss in detail the limitations of standard methods i.e. creatinine clearance and formulas in reflecting renal function. Several studies observed that estimated GFR does not properly reflect renal function in diabetes as well as in other clinical conditions. This portends severe consequences in clinical practice and research. Also, during the last decade, several new markers of renal disease in diabetic nephropathy have been described. We will discuss the relevance of novel markers of tubular damage, lipotoxicity, inflammation, microRNA among others in diabetic renal disease
Course content