Diabesity in renal transplantation


Post-Transplant Diabetes Mellitus (PTDM) and obesity are frequent complications after renal transplantation. PTDM affects up to 30% of renal transplant recipients, which doubles the prevalence of type 2 diabetes observed in the general population. The consequences of PTDM are severe: it is associated with a reduced patient survival, high risk of infections and cardiovascular disease, diminishes quality of life and increases health care expenditure. Obesity, particularly associated with metabolic syndrome -metabolically unhealthy obesity- is frequent after transplantation and is associated with increased risk for allograft dysfunction. In this CME we will evaluate diverse aspects of PTDM and obesity including: pathogenesis, impact, long-term evolution and treatment, as well as the consequences of obesity and metabolic syndrome in renal transplantation.

Course content

    1. Metabolic factors and allograft survival
    2. Metabolic syndrome and obesity after transplantation
    3. Clinical evolution of PTDM
    4. Pharmacological and non pharmacological risk factors for PTDM
    5. Pathogenesis of PTDM
    6. Clinical implications of obesity and PTDM
    7. Yhe importance of ogtt in clinical practice
    8. PTDM, a risk factor cardiovascular disease?
    9. Obesity after renal transplantation
    10. Cardiovascular disease after transplantation
    11. Similarities and differences between PTDM and type 2 diabetes
    12. Therapy and prevention of PTDM